Key result
Single-tube batch fractionation separates CK-MM and CK-MB isoenzymes in under 3 minutes.
Population
Serum samples, including a population free of heart disease
Comparison
Single-tube batch fractionation procedure on a… vs Current fractionation methods
Design
Other
Authors
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May accelerate CK-MB testing in labs; leaves open validation against modern assays before clinical use.
Describes a rapid and sensitive batch fractionation method for separating creatine kinase MB isoenzymes in serum.
L G Morin (1976) studied Free of heart disease. Single-tube batch fractionation procedure vs. Current fractionation methods was evaluated on Separation time and sensitivity for MB isoenzyme. A single-tube batch fractionation procedure separated creatine kinase MM and MB isoenzymes in under 3 minutes, detecting 4 U/L of MB isoenzyme.
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