Key result
Intermittent dobutamine infusion is linked to improved hemodynamics and clinical status in severe intractable HF.
Why the study?
Does intermittent dobutamine infusion improve clinical status and haemodynamics in elderly patients with severe intractable heart failure?
Case Report (n=10)
Does intermittent dobutamine infusion improve clinical status and haemodynamics in elderly patients with severe intractable heart failure?
Intermittent dobutamine infusion may be a useful and well-tolerated therapy for improving clinical status and haemodynamics in elderly patients with intractable heart failure.
Should not yet change practice; leaves open a role for intermittent dobutamine in refractory HF.
We describe the short- and long-term haemodynamic evolution of an elderly patient with severe intractable heart failure, who was treated with intermitted dobutamine infusion. This therapeutic regimen improved haemodynamic parameters and clinical status (New York Heart Association Functional Class) and prevented the hazardous cardiac, pulmonary and psychiatric disturbances the patient had suffered from with the previous therapeutic approach. No major side-effects were noted, except for a transient drop in arterial blood pressure. Subsequently, 9 other elderly patients were treated successfully with the same protocol. We propose the intermittent use of dobutamine in elderly patients with intractable heart failure, as a useful therapy for the improvement of their cardiac condition and general well-being.
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Brande et al. (2009) conducted a case report in Severe intractable heart failure (n=10). Intermittent dobutamine infusion was evaluated on Haemodynamic parameters and clinical status. Intermittent dobutamine infusion improved haemodynamic parameters and clinical status in 10 elderly patients with severe intractable heart failure.
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