Annual assessment of ECG intervals in patients with myotonic dystrophy type 1 using a mobile 6‑lead ECG device: TeleCheck-DM1

Figures

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  Fig. 1. Correlation and Bland – Altman analysis: Top row from left to right shows the Pearsons' r correlation between rECG and mECG for PQ interval. On the right side the Bland-Altman analyses are shown with corresponding mean differences and limits of agreement for PQ interval. In the bottom row from left to right Pearsons' r correlation between rECG and mECG are shown for QRS interval. On the right side Bland-Altman analyses are shown with mean difference and limits of agreement for QRS interval.

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  Fig. 2. Waveform analysis: ECG waveform analysis with side to side analyses of the rECG versus mECG showing the median beat analyses. In the top row from left to right it shows normal conduction, prolonged PQ interval, and wide QRS complex. In the bottom row it shows an underestimation of PQ interval with a wide QRS complex, overestimation of the QRS complex by mECG and underestimation of QRS complex by mECG.

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  Fig. 3. (A) Potential outpatient clinic visit reduction depending on the PQ threshold: Potential outpatient visit reduction based on PQ interval showing threshold sensitivity on the left y axis in blue versus potential outpatient reduction on the right y axis in red. The vertical lines show 95% sensitivity threshold (bold line) and the threshold when optimised for Youden's index (dashed line). (B) Potential outpatient clinic visit reduction depending on the PQ threshold for the DM1 cohort: Potential outpatient visit reduction based on PQ interval showing threshold sensitivity on the left y axis in blue versus potential outpatient reduction on the right y axis in red. The vertical lines show 95% sensitivity threshold (bold line) and the threshold when optimised for Youden's index (dashed line).