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September 10, 2026JAMA Cardiology

Dynamic Mitral Obstruction by a Left-Sided Cardiac Sarcoma

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Population

1 woman aged 54 years presenting with progressive exertional dyspnea and dynamic mitral obstruction by a…

Design

Case_report

Key result

A left-sided cardiac sarcoma caused dynamic mitral obstruction in a 54-year-old woman presenting with progressive exertional dyspnea.

Authors

FXFei XiaoBeijing Anzhen HospitalDLDaqi LiuCapital Medical UniversitySWSheng WangTibet University

Discussion

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Overview

Describes a clinical presentation of dynamic mitral obstruction caused by a left-sided cardiac sarcoma.

Key Points

  • Document a rare case of dynamic mitral valve obstruction secondary to a left-sided cardiac sarcoma in a middle-aged patient.
  • Evaluated a 54-year-old woman presenting with progressive exertional dyspnea through clinical and diagnostic assessment.
  • Identified a left-sided cardiac sarcoma causing dynamic mechanical obstruction across the mitral valve.
  • Attributed progressive exertional dyspnea to hemodynamic impairment resulting from tumor movement into the mitral orifice.

Structured PICO

P
Population
1 woman aged 54 years presenting with progressive exertional dyspnea and dynamic mitral obstruction by a left-sided cardiac sarcoma

Describes a clinical presentation of dynamic mitral obstruction caused by a left-sided cardiac sarcoma.

Cite This Study

Xiao et al. (2026) studied this question. A left-sided cardiac sarcoma caused dynamic mitral obstruction in a 54-year-old woman presenting with progressive exertional dyspnea.

synapsesocial.com/papers/6aa27bcf58559d80afc753f6https://doi.org/10.1001/jamacardio.2026.3266
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