Key result
Single-molecule detection techniques map myosin-head displacements and mechanochemical coupling to propose a myosin motor model.
Provides a review of single-molecule detection techniques applied to actomyosin mechanics and proposes a model for the myosin motor.
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Refines myosin motor model from single-molecule data; leaves open translation to cardiac contractility or therapies.
Yanagida et al. (2000) reported a review. Single-molecule detection techniques have allowed the accurate determination of myosin-head-induced displacements and mechanochemical coupling, leading to a proposed model of the myosin motor.
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