Key result
Pre-stent thrombus linked to ~450% higher odds of acute incomplete stent apposition in STEMI.
Why the study?
What are the predictors of incomplete stent apposition in STEMI patients treated with everolimus-eluting stents?
Cohort (n=114)
Yes
What are the predictors of incomplete stent apposition in STEMI patients treated with everolimus-eluting stents?
Odds Ratio: 5.5 (95% CI 1.1–26.9)
p-value: p=0.04
In STEMI patients treated with everolimus-eluting stents, pre-stenting thrombus and plaque characteristics assessed by OCT predict the occurrence of acute and late incomplete stent apposition.
Thrombus and lipid-rich plaque may heighten acute and late ISA risk after STEMI stenting; leaves open whether targeted lesion prep reduces persistence or events.
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Bernelli et al. (2016) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=114). Presence of thrombus before stent implantation vs. Absence of thrombus before stent implantation was evaluated on Acute incomplete stent apposition (ISA) (OR 5.5, 95% CI 1.1-26.9, p=0.04). The presence of thrombus before stent implantation independently predicted a 5.5-fold increased odds of acute incomplete stent apposition in STEMI patients treated with everolimus-eluting stents.
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