August 1, 1996Current Opinion in Lipidology
Hypoalphalipoproteinemia (low high density lipoprotein) as a risk factor for coronary heart disease
Key result
Low HDL is linked to increased CHD risk through direct atherogenic effects and associated lipoproteins.
Design
Review
Authors
Discussion
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Member takes
Implication
HDL assessment may refine coronary risk stratification with metabolic factors; leaves open causal targets for intervention trials.
PICO
P
Population
Coronary heart disease
E
Exposure / Comparator
Low high density lipoprotein (HDL) levels
O
Primary Outcome
Acute coronary events
Low HDL is a powerful predictor of acute coronary events due to multiple potential atherogenic mechanisms and associations with other risk factors.
Cite This Study
Vega et al. (1996) conducted a review in Coronary heart disease. Low high density lipoprotein (HDL) levels was evaluated on Acute coronary events. Low HDL levels are inversely related to the risk of coronary heart disease through direct atherogenic effects, association with other atherogenic lipoproteins, and other coronary risk factors.