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January 1, 2002Evidence-Based MedicineOpen Access

Review: angiotensin-converting enzyme inhibitors reduce the progression of non-diabetic renal disease

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Key result

ACE inhibitors reduce progression to ESRD in non-diabetic renal disease.

Authors

JBJeffrey S. Berns

Discussion

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Overview

ACE inhibitors merit first-line use in non-diabetic renal disease to delay ESRD; confirms renoprotection beyond BP reduction.

Study Design

Type

Meta-Analysis

PICO

P
Population
Meta-analysis of patient-level data from English-language randomized controlled trials evaluating ACE inhibitors versus control in patients with non-diabetic renal disease with at least 1 year of follow-up.
I
Intervention / Comparator
Angiotensin-converting enzyme (ACE) inhibitors vs Antihypertensive regimens not containing ACE inhibitors
O
Primary Outcome
End-stage renal disease (ESRD)

Cite This Study

Jeffrey S. Berns (2002) conducted a meta-analysis in Non-diabetic renal disease. Angiotensin-converting enzyme (ACE) inhibitors vs. Antihypertensive regimens not containing ACE inhibitors was evaluated on End-stage renal disease (ESRD). Angiotensin-converting enzyme inhibitors reduce the progression of non-diabetic renal disease.

synapsesocial.com/papers/6aa2d7cb74fc654bd0323ef0https://doi.org/10.1136/ebm.7.1.13
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Angiotensin-Converting Enzyme Inhibitors and Progression of Nondiabetic Renal Disease2001 · 1,115 citations
  2. 2Effect of Angiotensin-Converting Enzyme Inhibitors on Progression of Nondiabetic Renal Disease2002 · 40 citations
  3. 3The Effect of Angiotensin-Converting Enzyme Inhibitors on the Progression of Nondiabetic Renal Disease: A Pooled Analysis of Individual-Patient Data from 11 Randomized, Controlled Trials2001 · 19 citations
  4. 4Effect of Angiotensin-Converting Enzyme Inhibitors on the Progression of Nondiabetic Renal Disease1997 · 429 citations
  5. 5Angiotensin-converting enzyme inhibitors and progression of nondiabetic chronic renal disease1993 · 31 citations