Key result
Thoracoscopic radiofrequency ablation achieved 90% efficacy for sinus rhythm restoration at one year using a hybrid approach, but had a 30% complication rate.
Why the study?
The study evaluated the short- and mid-term results of thoracoscopic radiofrequency ablation combined with left atrial appendage resection for persistent atrial fibrillation.
Does thoracoscopic radiofrequency ablation combined with left atrial appendage resection improve sinus rhythm maintenance in patients with persistent atrial fibrillation?
Observational (n=10)
Does thoracoscopic radiofrequency ablation combined with left atrial appendage resection improve sinus rhythm maintenance in patients with persistent atrial fibrillation?
Thoracoscopic radiofrequency ablation for persistent AF has high efficacy (90% with a hybrid approach) but a significant complication rate (30%) compared to catheter ablation.
Complication rate of 30% advises caution against routine use; leaves open the need for RCTs versus catheter ablation in persistent AF.
Aim. Evaluation of short- and mid-term (up to one year) results of aт atrial fibrillation thoracoscopic radiofrequency ablation (TRFA) combined with left atrial appendage resection. Methods. 10 patients with persistent AF were included in the study. In 5 cases surgical ablation was performed as the primary intervention and in 5 cases surgery were preceded by two unsuccessful catheter procedures. Age of the patients was 54.4 (41; 63) years, duration of arrhythmic anamnesis – 5.6 (4.8; 6.8) years, anteroposterior size of the left atrium – 4.7 (45; 51 mm), LV ejection fraction – 63 (58; 68) %. TRFA included an isolation of right and left pulmonary veins, ablation lines along the roof and base of posterior wall of the left atrium, left atrial appendage resection. Results. In all cases of TRFA exit-block from the pulmonary veins was achieved. Among 10 procedures, a stable sinus rhythm was documented in 6 patients. In the remaining 4 patients AF was observed only in one case, and the other three demonstrated atypical atrial flutter, that given us a reason to repeat catheter procedures. In three cases of left atrial flutter, catheter ablation led to sinus rhythm restoration, and in case of AF and total sclerosis of left atrium a decision to refuse RF ablation was made. Complications were presented by a single case of bilateral phrenic nerve palsy, which required plication of the diaphragm, and two spontaneously resolved pulmonary atelectasis. Conclusion. The efficacy of atrial fibrillation thoracoscopic radiofrequency ablation during the follow-up period of one year was 90% regarding selective hybrid approach (thoracoscopic + catheter procedure). Procedure safety of TRFA was much lower than that of catheter ablation: the total number of small and big complications was 30%.
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Хоменко et al. (2020) conducted an observational in persistent atrial fibrillation (n=10). Thoracoscopic radiofrequency ablation (TRFA) combined with left atrial appendage resection was evaluated on Efficacy (sinus rhythm restoration) using a selective hybrid approach. Thoracoscopic radiofrequency ablation achieved 90% efficacy for sinus rhythm restoration at one year using a hybrid approach, but had a 30% complication rate.
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