Key result
Oral alcohol reduces small-vessel resistance in normal subjects but lacks large-vessel effects in arterial occlusive disease.
Why the study?
How does orally administered alcohol affect the hemodynamics of large and small vessels in patients with complete arterial occlusion or vasospasm compared to normal subjects?
Population
Patients with complete arterial occlusion and patients with vasospasm, and normal subjects
Comparison
Orally administered alcohol vs Normal subjects and baseline values prior to…
Design
Cross-sectional
Authors
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Alcohol shows no large-vessel effect in occlusive disease and should not change practice; leaves open selective role in vasospasm for prospective study.
Observational
How does orally administered alcohol affect the hemodynamics of large and small vessels in patients with complete arterial occlusion or vasospasm compared to normal subjects?
Orally administered alcohol demonstrates differential hemodynamic effects in peripheral vascular disease, improving resistance in vasospasm but lacking effect on collateral vessels in arterial occlusive disease.
Conrad et al. (1964) conducted an observational in Peripheral Vascular Disease. Orally administered alcohol vs. Normal subjects was evaluated on Hemodynamics of large and small vessels. Orally administered alcohol decreased small-vessel resistance in normal subjects but did not alter large-vessel hemodynamics in patients with arterial occlusive disease.
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