Key result
Ketamine-thiopental sodium combination resulted in no significant differences in hemodynamic variables compared to etomidate during anesthetic induction in CABG patients with low EF (p>0.05).
Why the study?
Does a ketamine-thiopental sodium combination compared to etomidate improve hemodynamic stability during anesthetic induction in CABG surgery patients with low ejection fraction?
Population
100 patients scheduled for elective coronary artery bypass graft surgery with low ejection fraction
Comparison
Ketamine-thiopental sodium combination for… vs Etomidate for anesthetic induction
Design
RCT, Randomly assigned, Double-blind
Follow-up
Up to 3 minutes after intubation
Authors
Loading...
Supports ketamine-thiopental as etomidate alternative in low-EF CABG induction; confirms hemodynamic equivalence in this RCT.
RCT (n=100)
Double-blind
randomly assigned
Does a ketamine-thiopental sodium combination compared to etomidate improve hemodynamic stability during anesthetic induction in CABG surgery patients with low ejection fraction?
p-value: p=>0.05
A ketamine-thiopental sodium combination provides comparable hemodynamic stability to etomidate during anesthetic induction in CABG patients with low ejection fraction.
Mohammad Reza Habibi (2014) conducted an RCT in Coronary artery disease with low ejection fraction undergoing CABG surgery (n=100). Ketamine-thiopental sodium combination vs. Etomidate was evaluated on Changes in hemodynamic variables (systolic/diastolic/mean arterial blood pressure and heart rate) (p=>0.05). Ketamine-thiopental sodium combination resulted in no significant differences in hemodynamic variables compared to etomidate during anesthetic induction in CABG patients with low EF (p>0.05).
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: