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January 1, 2013Journal of Clinical and Experimental DentistryOpen Access

Alternative to oral dicoumarin anticoagulants: Considerations in dental care

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Key result

NOACs show no greater risk than VKAs during invasive dental procedures, making suspension unnecessary.

Why the study?

Do new oral anticoagulants pose greater risks than conventional oral anticoagulants during invasive dental treatment?

Population

Patients receiving new oral anticoagulants (dabigatran, rivaroxaban, apixaban) undergoing dental care

Comparison

New oral anticoagulants vs Conventional oral anticoagulants

Design

Systematic_review

Authors

AMA. Mingarro-de-LeonBCB. Chaveli-Lopez

Discussion

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Member takes

Overview

Supports continuing NOACs without routine suspension for invasive dental procedures; confirms safety equivalence to conventional agents in Level 1 evidence.

Structured PICO

Do new oral anticoagulants pose greater risks than conventional oral anticoagulants during invasive dental treatment?

P
Population
A review of 76 articles evaluating the implications of new oral anticoagulants (dabigatran, rivaroxaban, apixaban) in patients undergoing dental care.
I
Intervention
New oral anticoagulants (dabigatran, rivaroxaban, apixaban)
C
Comparator
Conventional oral anticoagulants (vitamin K antagonists such as warfarin and acenocoumarol)
O
Outcome
Safety and need for suspension or modification of medication during invasive dental proceduressafety

New oral anticoagulants do not require routine suspension prior to invasive dental procedures, similar to conventional vitamin K antagonists.

Limitations

  • Limited clinical experience with new oral anticoagulants
  • Lack of a direct antidote
  • Lack of studies in specific patient populations
  • Limited randomized clinical trials in the dental care setting

Cite This Study

Mingarro-de-Leon et al. (2013) conducted a review in Patients receiving oral anticoagulants requiring dental care. New oral anticoagulants (dabigatran, rivaroxaban, apixaban) vs. Vitamin K antagonists was evaluated. New oral anticoagulants do not pose significantly greater risks than conventional oral anticoagulants during invasive dental treatment, and their suspension is not strictly required.

synapsesocial.com/papers/6aa39ed5229fb590e7c613eehttps://doi.org/10.4317/jced.51226
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Also Consider

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