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An intact incorporation of a 13CD3 group from [2-13C,2-2H3] acetate into the C(1) methyl group of terrein is established from the deuterium-decoupled 13C n.m.r. spectrum of the metabolite; a varying degree of exchange of label along the polyketide chain is detected.
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Garson et al. (1977) studied this question.
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