Key result
Potential drug-drug interactions affect ~82% of psychiatric patients, mostly at moderate or major severity.
Population
Psychiatric patients in Ayder referral hospital, Mekelle, Tigray, Ethiopia
Design
Cross-sectional
Authors
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May warrant DDI screening in psychiatric polypharmacy; leaves open clinical impact and mitigation strategies.
Cross-Sectional (n=216)
No
A high prevalence of potential drug-drug interactions, many of which carry risks of cardiotoxicity and QT prolongation, was identified among psychiatric patients, highlighting the need for close monitoring.
Mezgebe et al. (2015) conducted a cross-sectional in Psychiatric illness (n=216). Psychiatric medications was evaluated on Prevalence of potential drug-drug interactions. Among psychiatric patients, 81.8% had at least one potential drug-drug interaction, with the majority being of moderate or major severity.
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