Key result
Nexfin noninvasive pressure matches invasive radial pressure during reduced pulsatility within ~1 mmHg.
Why the study?
Does the Nexfin monitor accurately measure noninvasive arterial blood pressure compared to invasive measurement in patients with reduced arterial pulsatility?
Observational (n=28)
Does the Nexfin monitor accurately measure noninvasive arterial blood pressure compared to invasive measurement in patients with reduced arterial pulsatility?
Mean Difference: -1.3
The Nexfin monitor provides noninvasive blood pressure measurements that are similar to invasive radial artery pressures under conditions of reduced arterial pulsatility, such as during cardiopulmonary bypass or cf-LVAD support.
May support Nexfin as noninvasive BP alternative during reduced pulsatility; leaves open prospective validation before practice change.
Noninvasive blood pressure measurements are difficult when arterial pulsations are reduced, as in patients supported by continuous flow left ventricular assist devices (cf-LVAD). We evaluated the feasibility of measuring noninvasive arterial blood pressure with the Nexfin monitor during conditions of reduced arterial pulsatility. During cardiopulmonary bypass(CPB) in which a roller pump based or a centrifugal pump based heart-lung machine generated arterial blood pressure with low pulsatility, noninvasive arterial pressures (NAP)measured by the Nexfin Monitor were recorded and compared with invasively measured radial artery pressures (IAP).We also evaluated NAP in 10 patients with a cf-LVAD during a pump speed change procedure (PSCP). During CPB in 18 patients, the NAP-IAP average difference was -1.3 +/- 6.5 mmHg. The amplitude of pressure oscillations were 4.3 +/- 3.8 mmHg measured by IAP. Furthermore, in the cf-LVAD patients, increase in pump speed settings led to an increase in diastolic and mean arterial pressures (MAP) while the NAP acquired a sinusoidal shape as the aortic valve become permanently closed. In conclusion, NAP was similar to IAP under conditions of reduced arterial pulsatility. The device also measured the blood pressure waveform noninvasively in patients supported by a cf-LVAD.
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Martina et al. (2010) conducted an observational in Reduced arterial pulsatility (CPB or cf-LVAD) (n=28). Nexfin monitor (noninvasive arterial pressure) vs. Invasive radial artery pressure was evaluated on Average difference between noninvasive and invasive arterial pressures (Mean difference -1.3 +/- 6.5 mmHg). Noninvasive arterial pressure measured by the Nexfin monitor was similar to invasive radial artery pressure during reduced pulsatility, with an average difference of -1.3 +/- 6.5 mmHg.
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