Key result
Double diffusion gel precipitation detected two lines of precipitation (one group-specific and one serotype-specific) in sera of patients with ECHO infections.
Double diffusion gel precipitation can differentiate between group-specific and serotype-specific antibodies in ECHO virus infections.
Answers are grounded in this paper and cite their sources.
May support serologic distinction in enteroviral infections; leaves open clinical diagnostic adoption pending validation.
Double diffusion gel precipitation was used to detect antibodies in sera of patients suffering from ECHO infections. Two lines of precipitation were observed. One of them was apparently group specific and represented an antigen shared by human enteroviruses. The other line was serotype specific. The pattern of reactions with patient sera as well as animal immune sera confirmed the previous observation on serologic difference between prototype and Shropshire strains of ECHO 4.
No takes yet. Share an insight, caveat, or question.
Conant et al. (1966) studied ECHO infections. Double diffusion gel precipitation was evaluated on Detection of antibodies and precipitation lines. Double diffusion gel precipitation detected two lines of precipitation (one group-specific and one serotype-specific) in sera of patients with ECHO infections.
Synapse has enriched 10 related papers. Consider them for comparative context: