Key result
Visceral adiposity index was independently associated with the severity of coronary heart disease as measured by the Gensini score (OR 18.257).
Why the study?
Is visceral adiposity index associated with the severity of coronary heart disease in Chinese adults?
Cross-Sectional (n=95)
No
Is visceral adiposity index associated with the severity of coronary heart disease in Chinese adults?
Odds Ratio: 18.257 (95% CI 6.038–30.475)
p-value: p=0.005
Visceral adiposity index is strongly associated with the angiographic severity of coronary heart disease, particularly in diabetic patients.
VAI was associated with CHD severity, especially in diabetics; leaves open whether VAI cutoffs aid risk stratification in practice.
BACKGROUND: Visceral adiposity contributes to cardiometabolic risk, and visceral adiposity index (VAI) had significant correlation with visceral adiposity. We aimed to explore whether VAI was associated with cardiac structure and function and assess the impact of the cut-off points of VAI defining visceral adipose dysfunction (VAD) on the severity of coronary heart disease (CHD). METHODS: A total of 95 patients with CHD were divided into Control (nondiabetic CHD patients) and DM group (diabetic CHD patients). Then the two groups were respectively divided into VAD absent and VAD groups. Clinical, echocardiographic and coronary artery angiographic indexes were acquired to examine in relation to VAI. RESULTS: A significant increasing trend among the four groups of patients (Control + VAD absent, Control +VAD, DM + VAD absent and DM +VAD groups) were observed for waist circumference (WC), body mass index (BMI), systolic blood pressure (SBP), glucose, VAI and Gensini score (P<0.05 for all). The following variables were associated with VAI: total cholesterol, nonesterified fatty acid, Waist-Hip ratio and SBP. VAI was independently associated with Gensini score. CONCLUSIONS: The extent of CHD was more severe in diabetes, and VAI as a simple indicator of visceral adipose mass was strongly associated with the severity of CHD. The cut-off points of VAI used for defining VAD were more useful in diabetic CHD patients in identifying the severity of CHD.
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Han et al. (2014) conducted a cross-sectional in Coronary heart disease (n=95). Visceral adiposity index (VAI) was evaluated on Severity of coronary heart disease assessed by Gensini score (OR 18.257, 95% CI 6.038-30.475, p=0.005). Visceral adiposity index was independently associated with the severity of coronary heart disease as measured by the Gensini score (OR 18.257).
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