Key result
A 1-SD increase in brachial-ankle pulse wave velocity was associated with an 11% higher odds of sarcopenia in Chinese community-dwelling older adults (OR 1.11; 95% CI 1.04-1.20; P<0.01).
Why the study?
Previous studies linked arterial stiffness to skeletal muscle mass without considering muscle strength and physical performance, which are key components of sarcopenia.
Is arterial stiffness associated with sarcopenia in community-dwelling elderly?
Cross-Sectional (n=1,002)
Is arterial stiffness associated with sarcopenia in community-dwelling elderly?
Odds Ratio: 1.11 (95% CI 1.04–1.2)
p-value: p=<0.01
Higher arterial stiffness, measured by brachial-ankle pulse wave velocity, is associated with an increased risk of sarcopenia in older Chinese adults, particularly in men.
May support vascular screening for sarcopenia risk in older adults; leaves open causality and intervention effects.
BACKGROUND: Several previous researches had found artery stiffness associated skeletal muscle mass, but not considering muscle strength and physical performance, which also were compositions of sarcopenia. This study aims to reveal the relationship of artery stiffness and sarcopenia using the Asian Working Group for Sarcopenia criteria. METHODS: Study was performed on 1002 Chinese community dwelling participants aged ≥65 years from November 2016 to March 2017. Body composition, muscle strength, physical performance, and brachial-ankle pulse wave velocity (baPWV) considering as artery stiffness index were measured. RESULTS: In multiple regression analysis, baPWV was associated with handgrip (β=-0.13, P=0.04) and Relative skeletal muscle mass index (ASM/Ht2) (β=-0.02, P<0.01), but not with 4-meter velocity (P=0.21). Multiple logistic regression analysis showed that 1-SD (3.50m/s) increased in baPWV was still associated with a 11% (CI, 4%-20%; P<0.01) higher odds of being sarcopenia. In the gender subgroup analysis, the relationship of baPWV and sarcopenia remain significant in men (OR, 1.23; 95% CI, 1.07-1.42, P<0.01), but not in women (P=0.07). CONCLUSIONS: High brachial-ankle pulse wave velocity is associated with sarcopenia in Chinese community-dwelling elderly, with gender differences.
No takes yet. Share an insight, caveat, or question.
Zhang et al. (2018) conducted a cross-sectional in Sarcopenia (n=1,002). Arterial stiffness (brachial-ankle pulse wave velocity) vs. Lower arterial stiffness was evaluated on Sarcopenia (OR 1.11, 95% CI 1.04-1.20, p=<0.01). A 1-SD increase in brachial-ankle pulse wave velocity was associated with an 11% higher odds of sarcopenia in Chinese community-dwelling older adults (OR 1.11; 95% CI 1.04-1.20; P<0.01).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: