Key result
Existing data support a blood pressure goal of <140/90 mm Hg in high-risk patients younger than 80 years, and a systolic goal of 140-145 mm Hg for those aged 80 years and older.
Why the study?
Does reducing blood pressure to <140/90 mm Hg prevent cardiovascular events in high-risk hypertensive patients?
Does reducing blood pressure to <140/90 mm Hg prevent cardiovascular events in high-risk hypertensive patients?
This review supports targeting a blood pressure of <140/90 mm Hg in high-risk hypertensive patients under 80 years of age to prevent cardiovascular events.
May guide age-stratified BP targets in high-risk hypertension; leaves open optimal elderly thresholds pending randomized trials.
Existing epidemiologic and clinical trial data suggest that the blood pressure in patients with hypertension at high risk for cardiovascular events because of coronary artery disease, diabetes mellitus, chronic kidney disease, stroke, or heart failure should be reduced to <140/90 mm Hg in patients younger than 80 years and the systolic blood pressure be reduced to 140-145 mm Hg if tolerated in patients aged 80 years and older. Studies from patients with coronary artery disease, diabetes mellitus, chronic kidney disease, stroke, and heart failure will be discussed that support a blood pressure goal of <140/90 mm Hg in patients younger than 80 years at high risk for cardiovascular events.
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Wilbert S. Aronow (2013) conducted a review in Hypertension at high risk for cardiovascular events. Blood pressure reduction to <140/90 mm Hg was evaluated. Existing data support a blood pressure goal of <140/90 mm Hg in high-risk patients younger than 80 years, and a systolic goal of 140-145 mm Hg for those aged 80 years and older.
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