Key result
Reducing blood pressure to < 140/90 mm Hg is supported for patients aged < 80 years with hypertension and high cardiovascular risk, while a systolic goal of 140-145 mm Hg is suggested for those ≥ 80.
Why the study?
Optimal blood pressure targets for patients with hypertension at high risk for cardiovascular events due to comorbidities remain to be clarified.
Epidemiologic and clinical trial data suggest that blood pressure in patients with hypertension who are at high risk for cardiovascular events because of coronary artery disease, diabetes, chronic kidney disease, stroke, or heart failure should be reduced to < 140/90 mm Hg in patients aged < 80 years, and that systolic blood pressure should be reduced to 140 to 145 mm Hg, if tolerated, in patients aged ≥ 80 years. Studies on patients with coronary artery disease, diabetes, chronic kidney disease, stroke, and heart failure are discussed, supporting a blood pressure goal of < 140/90 mm Hg in patients aged < 80 years who are at high risk for cardiovascular events.
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Wilbert S. Aronow (2012) conducted a review in Hypertension at high risk for cardiovascular disease. Blood pressure reduction to < 140/90 mm Hg was evaluated. Reducing blood pressure to < 140/90 mm Hg is supported for patients aged < 80 years with hypertension and high cardiovascular risk, while a systolic goal of 140-145 mm Hg is suggested for those ≥ 80.
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