Key result
Measurement of elastic moduli at multiple frequencies using ultrasound and remote cyclic actuation allowed for the estimation of arterial wall viscoelasticity to characterize atherosclerotic plaques.
A novel ultrasound-based method using remote cyclic actuation can measure arterial wall viscoelasticity, potentially improving the characterization of atherosclerotic plaque components like lipids and blood clots.
To characterize tissues in atherosclerotic plaques, we have developed a method, the phased tracking method, for measuring the strain (change in wall thickness) and elasticity of the arterial wall. However, some types of tissue, such as lipids and blood clots, cannot be discriminated from each other based only on elasticity due to the small difference in their elasticity. For more precise tissue characterization, we have measured the regional viscoelasticity. To obtain the viscoelasticity, in this study, elastic moduli at multiple frequencies were measured with ultrasound by generating the change in internal pressure due to remote cyclic actuation. Furthermore, the viscoelasticity of the arterial wall was estimated from the measured elastic moduli at multiple actuation frequencies.
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Hasegawa et al. (2004) studied Atherosclerotic plaques. Measurement of elastic moduli at multiple frequencies by remote actuation was evaluated on Viscoelasticity of the arterial wall. Measurement of elastic moduli at multiple frequencies using ultrasound and remote cyclic actuation allowed for the estimation of arterial wall viscoelasticity to characterize atherosclerotic plaques.
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