Key result
Recent respiratory infection linked to ~164% higher DVT risk in the following month.
Why the study?
Does recent respiratory infection increase the risk of venous thromboembolism in adults?
Population
Adults aged ≥18 years with a first-time diagnosis of deep-vein thrombosis or pulmonary embolism, and…
Comparison
Recent respiratory infection. vs No recent respiratory infection.
Design
Case-control
Follow-up
1 year lookback period
Authors
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Respiratory infection was associated with VTE risk; extends infection-thrombosis link but remains hypothesis-generating without randomized data.
Case-Control (n=33,438)
Does recent respiratory infection increase the risk of venous thromboembolism in adults?
Odds Ratio: 2.64 (95% CI 1.62–4.29)
Absolute Event Rate: 4% vs 2.3%
Recent respiratory infection is strongly associated with an increased risk of venous thromboembolism, suggesting a need for similar preventive considerations as for arterial events.
Clayton et al. (2011) conducted a case-control in Venous thromboembolism (DVT or PE) (n=33,438). Recent respiratory infection vs. No recent respiratory infection was evaluated on Deep-vein thrombosis (DVT) in the month following infection (OR 2.64, 95% CI 1.62-4.29). Recent respiratory infection was associated with a significantly increased risk of deep-vein thrombosis in the following month (adjusted OR 2.64; 95% CI 1.62-4.29).
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