Key result
Dual excitation increases LV volume slope factor by ~17% vs single excitation in a canine model.
Why the study?
Does dual excitation improve the accuracy and linearity of conductance-derived left ventricular volume estimates compared to single excitation in a mathematical model?
Does dual excitation improve the accuracy and linearity of conductance-derived left ventricular volume estimates compared to single excitation in a mathematical model?
Absolute Event Rate: 0.76% vs 0.65%
Dual excitation of a conductance-volume catheter improves the linearity and accuracy of left ventricular volume estimates in a mathematical model compared to conventional single excitation.
Enhances modeled LV volume linearity; leaves open in vivo validation before clinical conductance catheter use.
The conductance method employs a multi-electrode catheter to generate an electrical field and measure intracavitary segmental conductances. Left ventricular (LV) volumes are calculated using an algorithm which assumes the electrical field to be homogeneous. This assumption may be violated leading to a non-linear relation between conductance-derived and true volumes. In addition, this relation may vary between segments. A new method is introduced which uses a more homogeneous field. Volume estimates using the conventional single excitation and the new dual excitation method were compared in a mathematical model of a canine LV, which was varied over a large volume range. With single excitation the slope factors, relating conductance-derived and true volumes, varied from 0.50 to 0.76 between segments and was 0.65 for total LV volume. Using dual excitation the segmental slope variability was reduced (range: 0.74-0.77) and the slope factor for total volume increased to 0.76. The linearity of the relation between conductance-derived and true volume was improved with dual excitation and extended over a larger range.
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Steendijk et al. (1992) studied Left ventricular volume measurement. Dual excitation method vs. Conventional single excitation method was evaluated on Slope factor relating conductance-derived and true volumes for total left ventricular volume. Dual excitation of the conductance-volume catheter increased the slope factor for total left ventricular volume to 0.76 compared to 0.65 with single excitation in a canine mathematical model.
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