Key result
Impaired pre-pregnancy renal function in transplant recipients is linked to ~109% higher perinatal mortality.
Why the study?
What are the maternal and fetal outcomes of pregnancy in women with a prior renal transplant?
Population
Pregnant women who had renal transplants between 1965 and 1989 in Spain.
Comparison
Pregnancy after renal transplantation vs Women with normal renal function before…
Design
Cohort
Follow-up
Pregnancy and postpartum period
Authors
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Baseline renal function assessment informs perinatal risk counseling in transplant recipients; extends historical cohorts but warrants prospective validation with modern regimens.
Cohort (n=133)
Yes
What are the maternal and fetal outcomes of pregnancy in women with a prior renal transplant?
Pregnancy in renal transplant recipients is feasible but carries definite maternal and fetal risks, which are significantly increased if pre-pregnancy renal function is impaired.
Cararach et al. (1993) conducted a cohort in Pregnancy in renal transplant patients (n=133). Pregnancy after renal transplantation was evaluated on Frequencies of miscarriage, therapeutic abortion, preterm birth, fetal malformation, twins, stillbirths, neonatal deaths and loss of maternal renal function. Pregnancy in renal transplant recipients carries definite risks, with impaired pre-pregnancy renal function increasing perinatal mortality (142 vs 68 per 1000) and miscarriage (22% vs 8%).
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