Key result
Quinidine and diuretics successfully control VT and CHF in a child with cardiac sarcoidosis.
Case Report (n=1)
Cardiac sarcoidosis should be considered as an etiology for ventricular tachyarrhythmias in children, as early recognition is critical for managing multi-organ involvement.
Supports quinidine-diuretic control of pediatric cardiac sarcoidosis VT/HF; leaves open steroid timing and generalizability.
Cardiac involvement by systemic sarcoidosis is well known, but occurs rarely. It usually manifests as either heart block, heart failure due to direct myocardial involvement, or cor pulmonale. We present the case of a patient with cardiac sarcoidosis who had ventricular tachycardia and congestive heart failure. Although there was other organ system involvement, the cardiac manifestation was the first to become clinically apparent. Therapy consisted of quinidine sulfate to control the arrhythmias and chronic diuretic therapy to control congestive heart failure. Steroid therapy was initially associated with recurrence of the ventricular tachycardia and was discontinued. It was reinstituted 18 months later when other organ system involvement developed with no recurrence of the ventricular tachyarrhythmia. The patient responded well to therapy and is currently doing well. This case is presented to illustrate a somewhat unusual, but nevertheless important, etiology of ventricular tachyarrhythmias. The recognition of underlying sarcoidosis is critical because of the propensity for other organ system involvement by this disease process.
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Serwer et al. (1978) conducted a case report in Cardiac sarcoidosis with ventricular tachycardia and congestive heart failure (n=1). Quinidine sulfate, chronic diuretic therapy, and steroid therapy was evaluated on Clinical response (arrhythmia and heart failure control). Therapy with quinidine sulfate and diuretics successfully controlled ventricular tachyarrhythmia and congestive heart failure in a child with cardiac sarcoidosis.
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