Key result
DDD ICD and steroids linked to AV block resolution and arrhythmia prevention in cardiac sarcoidosis.
Case Report (n=1)
Implantation of a DDD pacer/ICD combined with steroid therapy successfully managed conduction abnormalities and ventricular tachycardia in a patient with cardiac sarcoidosis.
May support combined device and steroid therapy for AV block in cardiac sarcoidosis; leaves open need for controlled trials.
Arrhythmias in a Patient With Sarcoidosis. Sarcoidosis is a multisystemic granulomatous disease of unknown etiology; up to 27% of cases entail cardiac involvement. Conduction abnormalities and ventricular tachycardia are the most common arrhythmias and can cause sudden death. We describe a patient who developed cardiac sarcoidosis 9 years after undergoing surgery for neurosarcoidosis. He presented with 2:1 second-degree atrioventricular block. Ventricular tachycardia with 3 morphologies was induced by exercise stress test. A DDD pacer/implantable cardioverter defibrillator (ICD) was implanted, which prevented exercise-induced ventricular tachycardia in a follow-up stress test. Treatment with steroids was initiated. The AVB disappeared, and no further arrhythmias were documented at the 1-year follow-up.
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Serra et al. (2011) conducted a case report in Cardiac sarcoidosis (n=1). DDD pacer/ICD implantation and steroid therapy was evaluated on Arrhythmia recurrence and AV block resolution. Implantation of a DDD pacer/ICD and initiation of steroid therapy in a patient with cardiac sarcoidosis led to the resolution of AV block and prevention of further arrhythmias at 1-year follow-up.
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