Key result
Single pass lead VDD pacing achieves ~98% AV synchrony without observed oversensing.
Why the study?
Does a single pass lead VDD pacing system provide reliable atrial sensing and AV synchronous pacing in patients with heart block?
Observational (n=101)
Yes
Does a single pass lead VDD pacing system provide reliable atrial sensing and AV synchronous pacing in patients with heart block?
A single pass lead VDD pacing system provides adequate atrial signals that converge over the first year, ensuring reliable AV synchronous pacing in patients with heart block.
Supports single-pass VDD leads for high AV synchrony in heart block; leaves open randomized trials versus dual-lead systems.
The atrial sensing capabilities of a new single pass lead VDD pacing system (Pacesetter AddVent) were assessed in a prospective multicenter study of 101 implants during the period July 1994 through March 1996. The pacing lead (Pacesetter AV Plus) has a unique quadripolar 4-in-line connector and uses a pair of ring electrodes with an interelectrode spacing of 12 mm for atrial sensing. The mean age of the patients (51 men) was 73 years (range 19-91). Seventy-five patients had complete heart block; the others had 2:1 AV block. Wide variations were found in signal amplitude: mean P wave amplitude, measured over four cycles in the supine position, was 2.4 +/- 1.9 mV at implant, dropping to 1.9 +/- 1.7 mV predischarge, and remaining constant at follow-up but with a narrower range. Holter monitoring was undertaken in 24 patients, with a total of 550 monitored hours. Mean AV synchrony was 98.2% +/- 4.6% (excluding premature ventricular contractions), with 20 patients (83%) showing > 99% AV synchrony, with atrial sensing at 0.1 mV where needed. No oversensing was observed in any patient. There was a low incidence of atrial fibrillation (2%) and sinus bradycardia (0%). The findings show that the range of atrial signals, although wide initially, converges over the first year and remains adequate for reliable AV synchronous pacing.
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Papouchado et al. (1996) conducted an observational in Complete heart block or 2:1 AV block (n=101). Single pass lead VDD pacing system (Pacesetter AddVent) was evaluated on Atrial sensing capabilities (P wave amplitude and AV synchrony). The single pass lead VDD pacing system provided reliable AV synchronous pacing, achieving a mean AV synchrony of 98.2% with no observed oversensing.