Key result
Smoking high-nicotine cigarettes elevates arterial pressure, heart rate, and LVEDP in angina patients.
Why the study?
Does smoking high-nicotine cigarettes alter cardiovascular hemodynamics in patients with angina pectoris and coronary heart disease?
Population
10 patients with angina pectoris due to proved coronary heart disease
Design
Case_series
Authors
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High-nicotine smoking may worsen hemodynamics in angina; hypothesis-generating and should not yet change practice.
Does smoking high-nicotine cigarettes alter cardiovascular hemodynamics in patients with angina pectoris and coronary heart disease?
Smoking high-nicotine cigarettes acutely worsens cardiovascular hemodynamics by simultaneously increasing myocardial oxygen demand and interfering with oxygen delivery in patients with coronary heart disease.
Aronow et al. (1974) studied Angina pectoris due to proved coronary heart disease (n=10). Smoking of high-nicotine cigarettes was evaluated on Cardiovascular hemodynamics (arterial pressure, heart rate, left ventricular end-diastolic pressure, stroke index, PO2 levels). Smoking high-nicotine cigarettes significantly increased arterial pressure, heart rate, and left ventricular end-diastolic pressure, and decreased stroke index and PO2 levels in angina patients.
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