Key result
The 2C'3AB strip shows ~95% agreement with commercial ELISA in differentiating FMDV-infected from vaccinated animals.
The developed 2C'3AB-based immunochromatographic strip is a highly specific and sensitive tool for rapid on-site differentiation of foot-and-mouth disease infected from vaccinated animals.
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Supports 3AB-based DIVA assays for FMD surveillance; leaves open large-scale field validation across serotypes.
Wu et al. (2011) studied Foot-and-mouth disease (FMD) (n=387). 2C'3AB-based immunochromatographic strip vs. 3ABC antibody ELISA kit was evaluated on Coincidence rate with commercial 3ABC antibody ELISA kit. The 2C'3AB-based immunochromatographic strip demonstrated high coincidence rates (95.0% to 100%) with a commercial 3ABC ELISA kit in differentiating FMDV-infected from vaccinated animals.
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