Efficient glucose detection in anaerobic solutions using an enzyme-modified electrode designed to detect H2O2: implications for biomedical applications

The finding that a ‘first generation’ glucose oxidase modified poly(o-phenylenediamine) coated Pt electrode, designed to detect H2O2, responded to glucose in N2-saturated solutions with a sensitivity similar to that of air-saturated media is of cosiderable significance for the application of biosensors in biological systems where O2 availability is severely restricted.