Key result
Left atrial appendage occlusion with an Amplatzer cardiac plug had <1% major complications, zero procedural mortality, and a 65% reduction in actual versus predicted stroke rate over 38.5 months.
Why the study?
Does left atrial appendage occlusion with an Amplatzer cardiac plug safely reduce stroke risk in patients with atrial fibrillation?
Observational (n=114)
No
Does left atrial appendage occlusion with an Amplatzer cardiac plug safely reduce stroke risk in patients with atrial fibrillation?
Answers are grounded in this paper and cite their sources.
Left atrial appendage occlusion with an Amplatzer cardiac plug is safe and effectively reduces stroke risk compared to predicted rates in patients with atrial fibrillation.
This is a review of 114 patients with atrial fibrillation who had left atrial appendage occlusion with an Amplatzer cardiac plug over a nine-year period done by a single operator. This shows that the procedure can be safely performed with a very low rate of major complications (< 1%) and a zero procedural mortality rate. Long-term follow up over an average of 38.5 months showed a 65% reduction in actual versus predicted stroke rate. This is similar to that seen with oral anti-coagulants and other published trials and registries involving left atrial appendage occlusion.
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Abelson et al. (2021) conducted an observational in atrial fibrillation (n=114). Left atrial appendage occlusion with an Amplatzer cardiac plug vs. Predicted stroke rate was evaluated on Actual versus predicted stroke rate (65% reduction). Left atrial appendage occlusion with an Amplatzer cardiac plug had <1% major complications, zero procedural mortality, and a 65% reduction in actual versus predicted stroke rate over 38.5 months.
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