Key result
Insulin reverses long QT in aged insulin-resistant rats by accelerating repolarization via β3-adrenergic signaling.
Key points are not available for this paper at this time.
Does not support insulin for long QT in patients; leaves open β3-adrenergic KCNQ1 activation as a research target in insulin resistance.
-ARs signaling pathway and particularly affecting activated PKG.
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A 2022 study studied this question. Insulin reverses long QT in insulin-resistant aged rats by activating KCNQ1/KCNE1 currents and accelerating ventricular repolarization via the β3-adrenergic receptor signaling pathway.
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