Successful treatment of primary cutaneous angiosarcoma of the nose with sequential chemo- and radiotherapy

Figures

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  Fig. 1. Initial presentation of the tumor A-Clinical aspect of the angiosarcoma B-MRI T1 sequence aspect of the angiosarcoma before treatment.

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  Fig. 2. Histological characteristics of the angiosarcoma 2A: hematoxylin-eosin: atypical endothelial cells involving the dermis and surrounding atypical vascular spaces 2B: sarcomatous proliferation: atypical epithelioid cells 2C: immunohistochemistry: CD31 membranous expression of tumor cells 2D: immunohistochemistry: ERG nuclear expression of tumor cell.

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  Fig. 3. Clinical complete response after neo-adjuvant chemotherapy.

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  Fig. 4. Irradiation planification and dose distribution Purple margins: GTV Yellow line: CTV Brown line: PTV Red area: 57 Gy isodose Orange area: 54 Gy isodose Blue area: 20 Gy isodose Green area: 15 Gy isodose. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

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  Fig. 5. MRI T1 sequence aspect of the angiosarcoma after treatment.

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  Fig. 6. Clinical aspect two years after the treatment.