Key result
T2DM linked to ~44% higher esophagitis prevalence among patients with upper GI symptoms.
Why the study?
Type II diabetes mellitus has been described as a possible risk factor for gastroesophageal reflux disease, but the prevalence of GERD, the diagnostic accuracy of the Reflux Disease Questionnaire, and the role of autonomic neuropathy in symptomatic diabetic patients needed investigation.
Is the prevalence of GERD higher in Type II Diabetes Mellitus patients with upper gastrointestinal symptoms, and is the Reflux Disease Questionnaire accurate for diagnosis?
Cross-Sectional (n=90)
No
Is the prevalence of GERD higher in Type II Diabetes Mellitus patients with upper gastrointestinal symptoms, and is the Reflux Disease Questionnaire accurate for diagnosis?
Absolute Event Rate: 76.66% vs 53.33%
p-value: p=0.03236
Type II diabetes is associated with a higher prevalence of GERD in symptomatic patients, and the Reflux Disease Questionnaire is a sensitive diagnostic tool in this population.
Gastrointestinal symptoms are relatively common in clinical practice in patients with type II diabetes mellitus.type II DM has been described as possible risk factor for the development of gastroesophageal reflux disease, in this study we aim to detect the prevalence of GRED in symptomatic patients with type II DM , also to see the accuracy of reflex disease questionnaire ( RDQ) in the diagnosis of GERD in patients with type II DM in relation to the esophagogastroduodenoscopy finding and to study the relation of autonomic neuropathy to the prevalence and stages of GERD in diabetic patients .Method: A ninety patients with upper gastrointestinal symptoms was divided in to tow groups according to whether had type II DM or not and then each group involved in a two stage process (a ) -a RDQ , ( b) -OGD .And patients in the DM group underwent another step to detect diabetic neuropathy by a bed side clinical test .Results: The prevalence of esophagitis in this study was higher in the DM group .RDQ had a statistical significance in detecting esophagitis in the DM group .There is no relation of autonomic neuropathy to the prevalence of GERD in diabetic patients . .Conclusion: The prevalence of GERD was high in patients with type II DM , RDQ is a sensitive tool for the diagnosis of GERD in diabetic pateints , Autonomic neuropathy did not increase prevalence of esophagitis in diabetic patients .
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Maysam Riyadh (2020) conducted a cross-sectional in Upper gastrointestinal symptoms suggestive of GERD (n=90). Type II Diabetes Mellitus vs. Non-diabetic patients was evaluated on Prevalence of esophagitis diagnosed by esophagogastroduodenoscopy (p=0.03236). Type II diabetes mellitus was associated with a significantly higher prevalence of esophagitis compared to non-diabetic patients among those with upper gastrointestinal symptoms (76.66% vs 53.33%, p=0.03236).
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