Key result
Obesity, regardless of blood pressure, is linked to increased erythrocyte Na+-H+ exchanger activity.
Why the study?
Is erythrocyte Na+-H+ exchange activity increased in essential hypertension or obesity?
Cross-Sectional (n=62)
Is erythrocyte Na+-H+ exchange activity increased in essential hypertension or obesity?
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Erythrocyte Na+-H+ exchanger overactivity is associated with excess body weight rather than being a specific feature of essential hypertension.
Delva et al. (1993) conducted a cross-sectional in Essential hypertension and obesity (n=62). Obesity vs. Non-obese subjects was evaluated on Erythrocyte Na+-H+ exchanger activity. Erythrocyte Na+-H+ exchanger activity was significantly increased in obese subjects regardless of blood pressure, but not in non-obese hypertensive patients, correlating with body mass index.
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