Key result
BIS-guided sedation for TAVI is linked to ~39-minute shorter procedures vs general anesthesia.
Why the study?
Does BIS-guided sedation improve procedural outcomes and safety compared to general anesthesia in elderly patients undergoing transfemoral TAVI?
Population
113 elderly patients with severe aortic valve stenosis undergoing transfemoral transcatheter aortic valve…
Comparison
Bispectral index (BIS)-guided sedation vs General anesthesia
Design
Cohort
Follow-up
30 days
Authors
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May support BIS-guided sedation for transfemoral TAVI; hypothesis-generating and requires randomized confirmation.
Observational (n=113)
No
Does BIS-guided sedation improve procedural outcomes and safety compared to general anesthesia in elderly patients undergoing transfemoral TAVI?
Absolute Event Rate: 127.1% vs 165.9%
p-value: p=0.004
BIS-guided sedation is a feasible and safe alternative to general anesthesia for transfemoral TAVI, associated with shorter procedure times and reduced need for transfusions and catecholamines.
He et al. (2017) conducted an observational in Severe aortic valve stenosis (n=113). Bispectral index (BIS)-guided sedation vs. General anesthesia was evaluated on Procedure time (minutes) (p=0.004). BIS-guided sedation for transfemoral TAVI significantly reduced procedure time compared to general anesthesia (127.1 vs 165.9 min, P=0.004), with fewer red blood cell transfusions and catecholamines.
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