Key result
Genetic cardiomyopathies show massive hypertrophy and reduced systolic volume versus massive dilation in acquired forms.
Describes the pathophysiological and morphological differences between hypertrophic and dilated cardiomyopathies.
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Supports etiological distinction in cardiomyopathy assessment; leaves open etiology-specific therapeutic trials.
Massive hypertrophy Reduced systolic volume Increased ventricular stiffness Difficulties in filling Good pump function CONGESTIVE (Dilated) Moderate hypertrophy Massive dilation Increased systolic and diastolic volumes.Poor pump function.Mainly left ventricle ano septum Patchy distribution of disease.Genetic basis.Multifactorial syndrome.Uniform distribution of disease.Right and left ventricles.Usually acquired basis.
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J. F. Goodwin (1982) conducted a review in Cardiomyopathy. Cardiomyopathies present with distinct pathophysiological profiles, contrasting the massive hypertrophy and reduced systolic volume of genetic forms with the massive dilation of acquired forms.
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