Key result
Metabolic syndrome is associated with an increased mean intimal-medial thickness of the common carotid (0.98 vs. 0.92 mm, P<0.01), suggesting it affects vessel wall modeling.
Absolute Event Rate: 0.98% vs 0.92%
p-value: p=<0.01
This editorial highlights the association between metabolic syndrome and vessel wall remodeling, specifically increased carotid intimal-medial thickness.
The prevalence of metabolic syndrome in the adult population in developing countries, as it is currently conceived by the current definitions, has been estimated to range from 22 to 39 % and varies depending on the definition used and on ethnicity (1–3). Metabolic syn-drome is associated with future coronary heart disease events (4), and this forms the underlying basis for the study by Dineen et al. in this issue of Diabetes (5). Patients with metabolic syndrome have been shown to have an increased mean intimal-medial thickness (0.98 vs. 0.92 mm, P, 0.01) of the common carotid and an increase in the number of components of metabolic syn-drome, which is associated with an increasing trend in the mean intimal-medial thickness, suggesting that metabolic syndrome can effect vessel wall modeling (6). Defining the
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Mark G. Davies (2015) conducted an editorial in Metabolic syndrome. Metabolic syndrome vs. No metabolic syndrome was evaluated on Mean intimal-medial thickness of the common carotid (p=<0.01). Metabolic syndrome is associated with an increased mean intimal-medial thickness of the common carotid (0.98 vs. 0.92 mm, P<0.01), suggesting it affects vessel wall modeling.
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