Key result
Device-based treatments reducing sympathetic outflow show promise for managing resistant hypertension.
Why the study?
Resistant hypertension poses a significant global healthcare burden due to its association with increased cardiovascular disease morbidity and mortality.
Device-based treatments targeting sympathetic nervous system outflow show promising evidence in the management of resistant hypertension.
Promising evidence for device-based sympathetic modulation in resistant hypertension; leaves open confirmation in large randomized trials before practice change.
PURPOSE OF REVIEW: Resistant hypertension (RH) is characterized by persistently elevated blood pressure despite the concurrent use of three antihypertensive medications, including a diuretic, at optimal doses. This clinical phenomenon poses a significant burden on healthcare systems worldwide due to its association with increased cardiovascular disease morbidity and mortality. RECENT FINDINGS: Ongoing studies on device-based treatment of RH, with aim to reduce sympathetic nervous system outflow, have shown promising evidence in management of RH which may in turn decrease the incidence of composite cardiovascular outcome faced by the affected population. SUMMARY: This paper aims to provide a comprehensive overview of RH, and review some of the diagnostic and therapeutic approaches in management of RH.
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Shariati et al. (2024) conducted a review in Resistant hypertension. Device-based treatment was evaluated. Device-based treatments aiming to reduce sympathetic nervous system outflow show promising evidence in the management of resistant hypertension.
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