Key result
Monophasic subtype and metastasis at presentation are linked to worse overall survival in synovial sarcoma.
Why the study?
What are the independent prognostic factors for overall and progression-free survival in patients with synovial sarcoma?
Population
41 consecutive patients with synovial sarcoma
Design
Cohort
Follow-up
January 1997 to March 2008
Authors
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Monophasic subtype and metastasis flag higher-risk synovial sarcoma; leaves open whether they should guide therapy intensity in prospective trials.
Cohort (n=41)
What are the independent prognostic factors for overall and progression-free survival in patients with synovial sarcoma?
Histologic subtype (monophasic) is the single most important independent prognostic factor for synovial sarcoma regardless of tumor stage.
Koh et al. (2009) conducted a cohort in Synovial sarcoma (n=41). Prognostic factors (including histologic subtype and metastasis) was evaluated on Overall survival and progression-free survival. Monophasic histologic subtype and metastasis at presentation were independent prognostic factors for poorer overall survival in patients with synovial sarcoma.
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