Key result
Biological prostheses show no one-year survival difference versus mechanical valves for tricuspid replacement.
Why the study?
Does biological prosthesis compared to mechanical prosthesis improve survival or prevent reoperation in patients undergoing tricuspid valve replacement?
Cohort (n=58)
No
Does biological prosthesis compared to mechanical prosthesis improve survival or prevent reoperation in patients undergoing tricuspid valve replacement?
Absolute Event Rate: 70.2% vs 76.5%
p-value: p=0.18
In patients undergoing tricuspid valve replacement, there was no significant difference in one-year survival or reoperation rates between biological and mechanical valves, though bovine prostheses may be less suitable due to high closing volume and regurgitation.
No survival difference supports individualized prosthesis selection; leaves open randomized durability and reoperation comparisons.
BACKGROUND: Replacement of the tricuspid valve is uncommon. Prostheses specifically designed for this position are not available. Bovine, porcine as well as mechanical valve prostheses are currently used, however, the most suitable prosthesis type has not been defined. METHODS: We retrospectively analyzed all consecutive patients who underwent tricuspid valve replacement (TVR) at the Medical University of Vienna from 1996 to 2014. Baseline patient characteristics, prosthesis type, and postoperative outcome data were collected. RESULTS: A total of 58 patients underwent TVR. Forty-one patients (71%) received biological (18 bovine, 23 porcine), and 17 patients (29%) mechanical prostheses. One-year survival (70.2% vs. 76.5%, P=0.18), and freedom from reoperation at one year (86.3% vs. 94.1%, P=0.35) was not significantly different bioprostheses and mechanical valves. Freedom from reoperation rates for bovine versus porcine prostheses (one-year: 88.2% vs. 84.4%, P=0.145) were also not significantly different. However, three bovine prosthesis had to be reoperated due to high-grade central regurgitation without any signs of endocarditis or structural valve degeneration. CONCLUSIONS: There is a lack of clinical trials on tricuspid valve replacement and no specific guidelines for the choice of prosthesis. In the current study we have not identified significant differences in mortality between mechanical and biological valves. However, bovine prostheses seem less suitable for the tricuspid position due to the high closing volume with consecutive severe postoperative regurgitation.
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Wiedemann et al. (2018) conducted a cohort in Tricuspid valve replacement (n=58). Biological prostheses vs. Mechanical prostheses was evaluated on One-year survival (p=0.18). Biological and mechanical prostheses for tricuspid valve replacement showed no significant difference in one-year survival (70.2% vs. 76.5%, P=0.18).
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