Key result
Patients after mitral repair without a prosthesis had a mean 1.05 cm2 larger LVOT orifice and an 8.0 degree larger MB angle at early systole compared to normal subjects.
Why the study?
How does mitral repair without a prosthesis affect the geometry and dynamics of the mitral annulus compared to normal subjects?
Observational (n=14)
How does mitral repair without a prosthesis affect the geometry and dynamics of the mitral annulus compared to normal subjects?
Absolute Event Rate: 49.5% vs 41.9%
After mitral repair without a prosthesis, the mitral annulus and LV base show near-normal size and flexible change, but a larger LVOT orifice and higher MB angle at early systole may weaken anterior mitral leaflet chordal tension.
The study of systolic changes in both the inflow and outflow of the left ventricle after mitral repair elucidates the geometric characteristics after surgery. The study included eight normal subjects and six patients after mitral repair without a prosthesis. The left ventricular (LV) base, consisting of both mitral valve annulus (MVA) and left ventricular outflow tract (LVOT) orifice, was reconstructed from magnetic resonance images. The angle between the planes of the MVA and LV base (MB angle), and the proportionate share of the LVOT at the LV base were calculated. After mitral repair, both the MVA and LV base became almost normal in size, showing flexible change (i.e., contraction and dorsiflexion) in the MVA and contraction of the LV base in systole. Compared with the normal heart at 100 ms delay from the electrocardiogram R wave, the hearts of the patients at the same phase had a mean 1.05 cm2 larger LVOT orifice, resulting in a mean 8.0 degree larger MB angle. Furthermore, the LVOT orifice occupied a mean of 49.5% of the LV base (41.9% in normal subjects). We hypothesize that the higher MB angle at early systole may weaken the tension of the chordae of the anterior mitral leaflet.
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Komoda et al. (2002) conducted an observational in Mitral repair (n=14). Mitral repair without a prosthesis vs. Normal subjects was evaluated on Proportionate share of the left ventricular outflow tract (LVOT) orifice at the LV base. Patients after mitral repair without a prosthesis had a mean 1.05 cm2 larger LVOT orifice and an 8.0 degree larger MB angle at early systole compared to normal subjects.
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