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September 1, 2026One HealthOpen Access

Hepatitis E virus genotype 3 RNA occurs in ~4% of sampled pigs in Senegal.

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Why the study?

Data on the epidemiology of hepatitis E virus in Senegal are limited, despite the emergence of a human epidemic in 2014.

Population

1600 pigs in Senegal immediately after slaughter

Design

Cross-sectional study

Key result

Hepatitis E virus RNA was detected in 4.3% of 1,600 sampled pigs in Senegal, with all sequenced strains being genotype 3, and 76.6% of RNA-negative samples showing anti-HEV antibodies.

Authors

BSBacary Djilocalisse SadioMJMamadou Malado JallowASAbdourahmane Sow

Discussion

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Overview

Supports potential zoonotic HEV transmission risk from pigs in Senegal; hypothesis-generating for human surveillance studies.

Study Design

Type

Cross-Sectional (n=1,600)

Structured PICO

P
Population
1,600 pigs sampled immediately after slaughter in Senegal between September 2018 and December 2019 to assess HEV prevalence.
O
Outcome
Prevalence, molecular characteristics, and seroprevalence of hepatitis E virus (HEV)surrogate

Pigs are an important reservoir of HEV genotype 3 in Senegal, indicating a potential risk of zoonotic transmission.

Cite This Study

Sadio et al. (2026) conducted a cross-sectional in Hepatitis E virus (HEV) (n=1,600). Hepatitis E virus (HEV) exposure was evaluated on HEV RNA detection. Hepatitis E virus RNA was detected in 4.3% of 1,600 sampled pigs in Senegal, with all sequenced strains being genotype 3, and 76.6% of RNA-negative samples showing anti-HEV antibodies.

synapsesocial.com/papers/6aa5a96b5becb0bc28eec546https://doi.org/10.1016/j.onehlt.2026.101557
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Detection of Hepatitis E Virus (HEV) in Pork Sold in Saint-Louis, the North of Senegal2024 · 5 citations
  2. 2Hepatitis E Seroprevalence and Detection of Genotype 3 Strains in Domestic Pigs from Sierra Leone Collected in 2016 and 20172024 · 6 citations
  3. 3Screening for Hepatitis E virus (HEV) in slaughtered pig for meat in Uyo using both serological and molecular methods and assessing their public health appraisal2024
  4. 4Investigating animal reservoirs for hepatitis E virus in Bangui, Central African Republic2024 · 6 citations
  5. 5Prevalence, Genetic Diversity, and Quantification of the RNA Genome of the Hepatitis E Virus in Slaughtered Pigs in Serbia2024 · 3 citations