Key result
DSE yields a lower positive predictive value for detecting asymptomatic CAD versus SPECT.
Why the study?
Does dobutamine stress echocardiography improve the detection of asymptomatic coronary artery disease compared to thallium-201 SPECT and exercise testing in asymptomatic diabetic patients?
Population
56 asymptomatic diabetic patients, mean age 60, 66% male, having at least three added risk factors, without…
Comparison
Dobutamine stress echocardiography with maximum… vs Thallium-201 single-photon emission computed…
Design
Cohort
Authors
Loading...
Supports dobutamine stress echocardiography as feasible alternative for silent ischemia screening in diabetes; leaves open need for randomized outcome trials versus SPECT.
Observational (n=56)
Does dobutamine stress echocardiography improve the detection of asymptomatic coronary artery disease compared to thallium-201 SPECT and exercise testing in asymptomatic diabetic patients?
Absolute Event Rate: 69% vs 75%
Dobutamine stress echocardiography is a feasible and effective alternative to thallium-201 SPECT for detecting silent myocardial ischemia in high-risk asymptomatic diabetic patients.
Penfornis et al. (2001) conducted an observational in Silent myocardial ischemia in diabetes (n=56). Dobutamine stress echocardiography (DSE) vs. Thallium-201 SPECT coupled with exercise stress testing (EST) was evaluated on Positive predictive value for detecting asymptomatic coronary artery disease. Dobutamine stress echocardiography had a positive predictive value of 69% (4 false negatives) compared to 75% (8 false negatives) for 201Tl SPECT in detecting asymptomatic coronary artery disease.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: