Key result
IV adenosine is linked to higher heart rates than oral dipyridamole with no significant side effect differences.
Why the study?
Does intravenous adenosine compared to oral dipyridamole cause different hemodynamic changes or adverse effects during myocardial perfusion scintigraphy in patients with suspected coronary artery disease?
Observational (n=65)
Does intravenous adenosine compared to oral dipyridamole cause different hemodynamic changes or adverse effects during myocardial perfusion scintigraphy in patients with suspected coronary artery disease?
Intravenous adenosine produces a greater increase in heart rate compared to oral dipyridamole during myocardial perfusion scintigraphy, with a similar safety profile and blood pressure response.
Answers are grounded in this paper and cite their sources.
Similar side-effect profile but greater heart-rate increase with adenosine; leaves open effects on imaging quality or patient selection in MPS.
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Yanarateş et al. (2016) conducted an observational in Suspected coronary artery disease (n=65). Intravenous adenosine vs. Oral dipyridamole was evaluated on Occurrence of at least one side effect. Intravenous adenosine resulted in a non-significant difference in side effects compared to oral dipyridamole (68% vs 46%) but caused a significantly greater increase in heart rate.
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