Why the study?
Polycystic ovary syndrome is the most common endocrinological problem causing irregular menstruation in women of reproductive age, prompting the search for novel inflammatory markers in PCOS.
Do monocyte HDL ratio and neutrophil lymphocyte ratio serve as diagnostic markers for polycystic ovary syndrome?
Population
100 cases diagnosed with PCOS and 100 controls
Comparison
PCOS cases vs controls, stratified by BMI
Design
Case-control study
Key result
Monocyte HDL ratio >10.139 and Neutrophil lymphocyte ratio >1.7 had diagnostic value for polycystic ovary syndrome, with levels significantly higher in cases than controls (P<0.05).
Authors
Loading...
Novel inflammatory markers in PCOS are hypothesis-generating; leaves open clinical utility pending validation in larger prospective studies.
Case-Control (n=200)
Do monocyte HDL ratio and neutrophil lymphocyte ratio serve as diagnostic markers for polycystic ovary syndrome?
p-value: p=<0.05
Monocyte HDL ratio and neutrophil lymphocyte ratio are elevated in PCOS independent of obesity and may serve as novel diagnostic markers for the disease.
Minnalkodi et al. (2022) conducted a case-control in Polycystic ovary syndrome (PCOS) (n=200). Polycystic ovary syndrome (PCOS) vs. Healthy controls was evaluated on Monocyte HDL ratio and Neutrophil lymphocyte ratio (p=<0.05). Monocyte HDL ratio >10.139 and Neutrophil lymphocyte ratio >1.7 had diagnostic value for polycystic ovary syndrome, with levels significantly higher in cases than controls (P<0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: