Key result
Fasting insulin, insulin secretion, and sensitivity do not correlate with arterial pressure in essential hypertension.
Why the study?
Is there an association between insulin resistance or plasma insulin levels and blood pressure values in patients with essential hypertension?
Cross-Sectional (n=49)
Is there an association between insulin resistance or plasma insulin levels and blood pressure values in patients with essential hypertension?
The study found no significant correlation between insulin resistance or hyperinsulinemia and blood pressure in patients with essential hypertension, challenging the hypothesis that insulin directly regulates arterial pressure in this population.
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Challenges insulin-BP hypothesis in mild hypertension; leaves open any role in larger or severe cohorts.
Cabezas-Cerrato et al. (1997) conducted a cross-sectional in essential arterial hypertension (n=49). Insulin resistance and hyperinsulinaemia was evaluated on Correlation with arterial pressure. Fasting insulinaemia, glucose-induced insulin secretion, and insulin sensitivity did not correlate significantly with arterial pressure in 49 patients with mild or moderate essential hypertension.
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