What is the clinical evidence from this study?

Study design: Cohort. Population: Mitral annulus calcification (n=63). Intervention: Mitral annulus calcification. Primary outcome: Stroke.

What does this research mean for the field?

Mitral annulus calcification is primarily a marker of generalized calcific atherosclerosis rather than a direct embolic source of stroke. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 1, 1984StrokeOpen Access

Risk of stroke in patients with mitral annulus calcification.

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Key result

Mitral annulus calcification links to a ~5% fatal stroke rate, reflecting atherosclerosis rather than embolism.

n=63

Authors

AFA J FurlanWestern Michigan University ACA R CraciunUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș ESErnesto E. SalcedoThe University of Texas Southwestern Medical Center

Discussion

Member takes

Overview

MAC should not prompt anticoagulation for presumed embolism; leaves open its value as an atherosclerosis marker in risk models.

Study Design

Type

Cohort (n=63)

PICO

Population

63 patients with mitral annulus calcification followed for an average of 3.4 years.

Exposure / Comparator

Mitral annulus calcification

Primary Outcome

Stroke

Limitations

Embolic stroke due to MAC is difficult to prove due to coexistent atherosclerosis.

Cite This Study

Furlan et al. (1984) conducted a cohort in Mitral annulus calcification (n=63). Mitral annulus calcification was evaluated on Stroke. Mitral annulus calcification was associated with a 5% rate of fatal stroke over 3.4 years, none attributed to embolism, suggesting it is a marker of atherosclerosis rather than an embolic source.

synapsesocial.com/papers/6aa636d1fff38ca398dd46b3 https://doi.org/10.1161/01.str.15.5.801

Topics

Echocardiography

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September 1, 1984StrokeOpen Access

Risk of stroke in patients with mitral annulus calcification.

View Full Paper

Ask AI

Bookmark

Key result

Mitral annulus calcification links to a ~5% fatal stroke rate, reflecting atherosclerosis rather than embolism.

n=63

Authors

Discussion

Member takes

Overview

MAC should not prompt anticoagulation for presumed embolism; leaves open its value as an atherosclerosis marker in risk models.

Study Design

Type

Cohort (n=63)

PICO

Population

63 patients with mitral annulus calcification followed for an average of 3.4 years.

Exposure / Comparator

Mitral annulus calcification

Primary Outcome

Stroke

Limitations

Embolic stroke due to MAC is difficult to prove due to coexistent atherosclerosis.

Cite This Study

synapsesocial.com/papers/6aa636d1fff38ca398dd46b3 https://doi.org/10.1161/01.str.15.5.801

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Topics

Echocardiography

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