Key result
Anticoagulation resolves a large mobile thrombus on a calcified mitral annulus following recurrent cerebral embolism.
Case Report (n=1)
Highlights that superimposed thrombus on mitral annular calcification is an under-appreciated potential cause of systemic thrombo-embolism that may resolve with anticoagulation.
May support anticoagulation for thrombus on calcified mitral annulus; leaves open need for prospective confirmation before practice change.
Mitral annular calcification (MAC) has been considered a predisposition and an association of thrombo-embolic disease. Superimposed thrombus on MAC is under-appreciated as a potential cause of systemic thrombo-embolism. This report describes an elderly gentleman, who had recurrent cerebral embolism and in one of the episodes, a large mobile thrombus was detected on the ventricular surface of calcified mitral annulus. The thrombus disappeared after initiation of anti-coagulation.
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Mohan et al. (2016) conducted a case report in Recurrent cerebral embolism and mitral annular calcification with superimposed thrombus (n=1). Anti-coagulation was evaluated on Disappearance of thrombus. Initiation of anti-coagulation led to the disappearance of a large mobile thrombus on the ventricular surface of a calcified mitral annulus in an elderly man with recurrent cerebral embolism.
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