Key result
Dense mitral annular calcification linked to mobile LV thrombus despite normal LV function and sinus rhythm.
Why the study?
Superimposed thrombus formation on mitral annular calcification has not been well described as a possible mechanism for thrombo-embolic disease associated with MAC.
Case Report (n=3)
Highlights a rare presentation of mobile LV thrombus superimposed on severe mitral annular calcification as a potential mechanism for thrombo-embolic disease in patients with otherwise normal cardiac function and rhythm.
Mitral annular calcification (MAC) has been considered a risk factor for thrombo-embolic disease. Superimposed thrombus formation on MAC has not been well described as a possible underlying mechanism for this association. We report three patients with mobile left ventricular (LV) thrombus arising from the LV aspect of severe calcified mitral annulus in the setting of normal LV function, mitral valve function, and sinus rhythm.
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Sia et al. (2009) conducted a case report in Mobile left ventricular thrombus with dense mitral annular calcification (n=3). Dense mitral annular calcification was evaluated on Mobile left ventricular thrombus formation. Dense mitral annular calcification can serve as a substrate for mobile left ventricular thrombus formation even in the presence of normal LV function, mitral valve function, and sinus rhythm.
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